The architectural design found in the buildings that house the programs and services of the Henry Street Settlement is as rich in history as the Settlement itself.  Spread throughout the Lower East Side of Manhattan, they act as both a guide to the growth and evolution of the social service reform movement, and as a timeline for American architecture.  Of the eighteen locations, four are recognized as significant historical landmark structures, and two have received awards for the Settlement's preservation efforts.

Henry Street Headquarters: 263, 265 and 267 Henry Street    Abrons Arts Center and Harry De Jur Playhouse: 466 Grand St.  281 East Broadway  301 Henry Street  Helen's House: 309 Henry Street  Montgomery and Madison Street  Baruch, FDR Drive, and East 9th Street  24 Avenue D and 888 East 6th Street  Camp Ralph and Rose Hittman